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An Integrated Approach for Statistical Genome Sequence Analysis between Genetic Datasets
Article Number: SIS085143AI141222
14th December, 2022
Author(s):
Hassan Mathkour, Muneer Ahmad, Hassan Mahmood khan
Abstract:
Genome Sequence Analysis for genetic datasets by using ORF (Open Reading Frames)
techniques is an interesting area of research for bioinformatics researchers nowadays. There is
a strong research focus on comparative analysis between genetic behaviors and diversity of
different species. Contrary to whole genome sequence analysis, scientists are now trying to
concentrate specifically on layered analysis to get a better insight of relevancy among genetic
datasets. This phenomenon will help to better understand species. An ORF statistical analysis
for genetic data-sets of species Chimera Monstrosa and Poly Odontidae is presented. For
completion of this analysis, we use a hybrid approach that combines a generic mechanism for
statistical analysis with specific approach designed for out performance. At first instance,
genetic datasets are refined for better usage at next level. These sets are then passed through
layers of filters that perform DNA to Protein translation. Statistical comparison is performed
during this translation. This layered architecture helps in better understanding of the degree of
similarity and differences in genomic sequences.