S.I.S

Scholar Indexing Society (S.I.S)
Donate

S.I.S

Scholar Indexing Society (S.I.S)
MetaScholar
Turnitin Packages

Welcome! Accelerate Your Discovery

Be a part of a committed society that is shaping the future of knowledge Search

2261
Indexed articles
1285
Archived project
23
Indexed Journals
201
Registered users
577
visits in 24hrs
348764
Total visit count
17
Hall of fame
67
Researchers
12
Sponsors

Case 4-2025: A 41-Year-Old Man with Syncope, Ankle Swelling, and Abnormal Chest Imaging

Article Number: SIS302985AI050525
5th May, 2025
Author(s):
Daniel Restrepo, Sadia Sultana, Sanjay Divakaran, Jeffrey A. Sparks
Abstract:

A 41-year-old man with a history of coronary artery disease presented with syncope, bilateral ankle swelling, fever, and inflammatory arthritis. Imaging revealed bilateral hilar lymphadenopathy, pulmonary nodules, and erythema nodosum, consistent with Löfgren’s syndrome, an acute manifestation of sarcoidosis. Cardiac evaluation ruled out significant myocardial involvement. The patient responded well to a tapering course of glucocorticoids, with resolution of symptoms and radiographic improvement. This case highlights the classic triad of Löfgren’s syndrome and underscores the importance of distinguishing sarcoidosis from infectious, malignant, and other autoimmune etiologies in patients with systemic inflammatory symptoms.

Keywords:
Löfgren’s syndrome Sarcoidosis Bilateral hilar lymphadenopathy Erythema nodosum Inflammatory arthritis Syncope Glucocorticoids Cardiac sarcoidosis Pulmonary nodules Autoimmune disease.
Share article
Share article
WhatsApp Email
Copy link
Download Full Text

Recommended Articles

What Is the Relative Value of a Baby?
Rachel Fleishman, M....
perinatal care, neonatal respiratory distress, U.S. healthcare inequities, relative value units (RVUs), Medicaid reimbursement, hospital closures, maternal mortality

This article, written from the perspective of a neonatologist, reflects on a newborn’s struggle to... 4 weeks ago

Way Stations in Progress — Burgeoning Treatment ...
Julie R. Ingelfinger...
IgA nephropathy, glomerulopathy, sodium-glucose cotransporter 2 inhibitors, targeted budesonide, sibeprenlimab, iptacopan, atrasentan, kidney function, proteinuria reduction, eGFR, clinical trials

IgA nephropathy, once considered a benign condition, is now recognized as the most common glomerulop... 4 weeks ago

Tumoral Melanosis
Deshan F. Sebaratnam...
tumoral melanosis, melanoma regression, immunotherapy response, dermoscopy-guided biopsy, melanin-laden macrophages, dermatologic surveillance

An 84-year-old man with a history of melanoma on the right forehead, complicated by in-transit metas... 4 weeks ago

Tubal Ectopic Pregnancy
Courtney A. Schreibe...
tubal ectopic pregnancy, pelvic inflammatory disease, maternal mortality, transvaginal ultrasound, methotrexate therapy, salpingectomy, reproductive health disparities

Tubal ectopic pregnancy occurs when a fertilized egg implants in the fallopian tube, posing a seriou... 4 weeks ago

Traveling Companions
Rachel K. Gardner, ...
secondary syphilis, septic arthritis, injection-drug use, MRSA, sexually transmitted infections, migratory polyarthritis, vancomycin, dalbavancin

This clinical problem-solving case discusses a 29-year-old man who presented with fever, chills, and... 4 weeks ago

Timing the Taming of Vascular Inflammation
Joseph Loscalzo, M.D...
vascular inflammation, acute myocardial infarction, colchicine therapy, spironolactone, endothelial dysfunction, fibrinolysis

This editorial examines vascular inflammation in atherothrombosis and assesses whether early anti-in... 4 weeks ago

Tirzepatide for Congenital Generalized Lipodystrop...
Svetlana Ten, M.D.; ...
congenital generalized lipodystrophy, AGPAT2 variant, severe insulin resistance, leptin deficiency, tirzepatide monotherapy, glucose

This correspondence details the use of tirzepatide, a once-weekly dual GLP-1/GIP agonist, in two pat... 4 weeks ago

The Rise of Private Equity in Health Care — Not...
Yashaswini Singh, Ph...
private equity in health care, financialization, global investments, hospital closures, medical regulations, market consolidation, health care transparency, policy interventions

Private equity investments in global health care have surged, reaching $446 billion between 2018 and... 4 weeks ago

The Man Who Lives in the Cardboard Box
Teva D. Brender, M.D...
medical ethics, compassion, homelessness, institutional responsibility, physician self-awareness, societal inequalities, human dignity

This reflective essay explores the complexities of compassion, moral responsibility, and self-awaren... 4 weeks ago

The Future of Gender-Affirming Care — A Law and ...
Daniel G. Aaron, M.D...
gender-affirming care, Cass Review, NHS policies, transgender healthcare, randomized controlled trials, informed consent, medical ethics

This article critiques the Cass Review, a report commissioned by England’s National Health Service... 4 weeks ago

The Death of an Unlikable Man
Mark Earnest, M.D., ...
medical ethics, patient care, difficult patients, physician bias, empathy, prejudice in healthcare, palliative reflection, hospital mortality, caregiver burden

This deeply reflective piece explores the ethical and emotional challenges faced by healthcare provi... 4 weeks ago

The Consequences of Silencing the "Voice of CD...
Sonja A. Rasmussen, ...
CDC, MMWR, public health communication, scientific integrity, H5N1 influenza, health advisories, political interference, Trump administration, NIH, FDA

This article examines the implications of a temporary halt on public communications from the Centers... 4 weeks ago

Routine Spironolactone in Acute Myocardial Infarct...
anjit S. Jolly, M.D....
myocardial infarction, spironolactone, mineralocorticoid receptor antagonist, heart failure, CLEAR trial, cardiovascular mortality,

Spironolactone, a mineralocorticoid receptor antagonist, is established in the treatment of heart fa... 4 weeks ago

Pleural Paragonimiasis
Lin Wang, M.D.; Niaz...
pleural paragonimiasis, lung fluke infection, Paragonimus mexicanus, eosinophilia, pleural effusion, parasitic lung disease

A 17-year-old boy from El Salvador was diagnosed with pleural paragonimiasis after a routine chest r... 4 weeks ago

Pulling Out the Rug on Informed Consent — New L...
Kristen Underhill, ...
informed consent, medical litigation, gender-affirming care, healthcare restrictions, malpractice risks, legislative impact, medical ethics, patient autonomy

Recent legislative efforts in multiple U.S. states have sought to limit access to gender-affirming c... 4 weeks ago

Plaques en Prairie Fauchée Tongue Lesions in Seco...
Jonathan P. Angel, ...
secondary syphilis, plaques en prairie fauchée, HIV infection, oral lesions, treponemal testing, rapid plasma reagin, penicillin therapy, infectious diseases

A 29-year-old man with well-controlled HIV infection presented with a painful, whitish discoloration... 4 weeks ago

Oral Manifestations of Pemphigus Vulgaris
Joseph Katz, D.M.D.;...
pemphigus vulgaris, oral lesions, autoimmune blistering disorder, IgG deposition, gingival biopsy, mucocutaneous disease, steroid therapy, rituximab, immunosuppressant

A previously healthy 44-year-old woman presented with mouth ulcers and blistered lips persisting for... 4 weeks ago

One Size Fits … Some
Danielle Chammas, M....
medical education, patient communication, palliative care, emotional intelligence, psychotherapy techniques, cultural sensitivity, doctor-patient interaction

This article examines the challenges of applying standardized communication techniques in medical ed... 4 weeks ago

My Mother’s Choices
Hannah Kirsch, M.D
Medical aid in dying (MAID), palliative care, caregiver burden, patient autonomy, end-of-life decisions, physician ethics, metastatic cancer

In this deeply personal narrative, Dr. Hannah Kirsch, a neurointensivist and palliative care researc... 4 weeks ago

Middle Meningeal Artery Embolization and Nonacute ...
Peter Kan
Middle meningeal artery embolization, nonacute subdural hematoma, chronic subdural hematoma, recurrence, surgical adjunct, liquid embolic agent, anticoagulation

Nonacute subdural hematoma (SDH) is a growing concern among aging populations, particularly with inc... 4 weeks ago

Records : 20 of 2218 | Page : of 111 | Limit

Are you ready to amplify your academic presence and connect with a global network of researchers? Join the Scholar Indexing Society and elevate your research to new heights!

Close

Search SIS !

Articles, journal, project, hall of fame

Scholar Indexing Society
Close
Username or Email
Password
Reset password

Don't have an account? Register

Do you have an account already? Login

Copyright © Scholar Indexing Society All Rights Reserved.