Welcome! Accelerate Your Discovery

Be a part of a committed society that is shaping the future of knowledge Search

Pharmacotherapy of infertility in Ghana: retrospective study at the cape coast teaching hospital

Article Number: SIS892365AI080123
8th January, 2023
Author(s):
Stephen Mensah Arhin, Kwesi Boadu Mensah, Evans Agbeno, Vitus Sambo Badii, Charles Ansah
Abstract:

Background

Infertility is a major challenge for couples globally. Due to low income levels and the high cost of other assisted reproductive techniques, pharmacotherapy remain the major first line treatment option for infertility in Sub-Saharan Africa.

Objective

The aim of this study was to assess the prevalence of infertility as well as the effectiveness and success achieved following infertility pharmacotherapy at the Cape Coast Teaching Hospital in Ghana.

Methods

This study was a retrospective observational study of 825 couples attending infertility clinic at the hospital.

Results

Prevalence of infertility at the study center was estimated to be 12.3%. Treatment mainly involved the use of clomiphene citrate, antioxidants, herbo-mineral drugs (Ayurveda), multivitamin and antibiotics. Pharmacotherapy resulted in successful conception in one out of every five couples (19.4%; n = 160). Secondary infertility, although more prevalent in the study population (44.8%; n = 370), had lower conception rates during pharmacotherapy than primary infertility (15% vs 26.2%). Age, kind of infertility, employment status but not educational level were significantly associated with pharmacotherapy success. In ovulation induction, clomiphene citrate plus folic acid and vitamin E adjuncts improved ovulation rates during cycle treatments compared to clomiphene citrate alone. Pharmacotherapy of idiopathic infertility (39%, n = 323) was a major challenge with very limited success rates. Interestingly, it was noted that treating couples or female partners only for idiopathic infertility resulted in higher success rates than treating the male partner only. Again, 90-day treatment regimen doubled conception rates when compared with corresponding 30-day treatment regimen. However, zinc sulfate even in short term treatment regimens (30 days) enhanced conception rates in idiopathic infertility.

Conclusions

Prevalence of infertility was estimated to be about 12.3%. One out of every five infertile couples achieved success with pharmacotherapy. Factors such as age, type of infertility, employment status, but not education were significantly associated with treatment success.

Share article

Recommended Articles

The Impact of HIV Decriminalization Policies on Pu...
Isaac Buabeng Bempon...
HIV decriminalization, public health outcomes, stigma reduction, harm reduction programs, healthcare access

HIV decriminalization policies have emerged as a pivotal strategy in addressing the global HIV epid... 3 weeks ago

Suicide and Suicide Attempts among Patients Attend...
Dennis Bomansang Dal...
Attempted suicide, Suicide, prevalence, attempted suicide

Suicide and suicidal attempts have become a public health concern worldwide as it is the second le... 1 month ago

The Impact of Exclusive Breastfeeding Practices on...
Isaac Buabeng Bempon...
Exclusive breastfeeding, Working mothers, Workplace support, Maternal well-being, Lactation policies

Exclusive breastfeeding is essential for optimal infant health, yet working mothers often face sign... 1 month ago

Exploring Communication Modes and Cultural Signifi...
Thomas Aazagsiba Aga...
Communication, communication modes, culture, soothsaying, cultural heritage.

This study delves into the communication modes and cultural importance of soothsaying practices in ... 2 months ago

The Impact of Performance Appraisal Systems on Emp...
Aminatu Osman, Veron...
Performance Appraisal Systems, Employee Motivation, Human Resource Management, Organizational Success, HR Decision-Making

This comprehensive review examines the impact of performance appraisal systems on employeemotivation... 3 months ago

Application of GIS and Multi-Criteria Decision An...
GIS; RS; QGIS; MCDA;...
GIS; RS; QGIS; MCDA; LULC

On March 15, 2018, the municipal boundaries of Berekum were divided, resulting in the per-urban town... 3 months ago

Balancing Innovation and Privacy: The Role of Inte...
Doris Amoako, Vida ...
Interactive Technologies, Team Dynamics, Virtual Collaboration, Technology, Acceptance Model (TAM), Data Privacy and Ethics

This review examines the influence of interactive technologies on team dynamics andperformance in or... 3 months ago

The Impact of Performance Appraisal Systems on Emp...
Aminatu Osman, Veron...
Performance Appraisal Systems, Employee Motivation, Human Resource Management, Organizational Success, HR Decision-Making

This comprehensive review examines the impact of performance appraisal systems on employee motivati... 3 months ago

The Impact of Internal Communication on Employee ...
Clement Damoah Ababi...
nternal Communication, Employee Performance, Credit Unions, Organizational Politi

This study examines the impact of internal communication on employee performance within  c... 3 months ago

The Impact of Internal Communication on Employee P...
Clement Damoah Ababi...
Internal Communication, Employee Performance, Credit Unions, Organizational Politics

This study examines the impact of internal communication on employee performance within credit unio... 3 months ago

The Role of Intrinsic and Extrinsic Motivational F...
Solomon Piilazaaya K...
Intrinsic Motivation, Extrinsic Motivation, Job Performance, Internal Auditors, Public Sector

This study investigates the influence of intrinsic and extrinsic motivational factors on job perfor... 3 months ago

Socio-Cultural and Healthcare Barriers to Timely A...
Emmanuel Asomaning, ...
Antenatal Care (ANC), Maternal Health, Socio-cultural Barriers, Health Service Accessibility, Wa East District, Ghana

This study investigates the factors influencing late initiation of antenatal care (ANC) among pregn... 3 months ago

The Influence of Organizational Culture on Employe...
Emmanuel Kwabena Opp...
Organizational Culture, Employee Performance, Knowledge Sharing, Ghanaian Enterprises, Hierarchical Structures

This study explores the influence of organizational culture on employee performance within Ghanaian... 3 months ago

Factors Influencing the Performance of Universal B...
Akentara Richard, Is...
Internal factors, external factors, bank performance, liquidity position, managerial competence

A strong banking or financial sector is a reflection of a strong economy. The banking industry in G... 4 months ago

The Role of Pastoral Care in the Rehabilitation of...
Isaac Bright Fosu Ku...
Pastoral care, inmate rehabilitation, Kumasi Central Prison, spiritual support, recidivism.

This study examines the role of pastoral care in rehabilitating inmates at Kumasi Central Prison, h... 4 months ago

The Efficacy of Performance Appraisal Systems in E...
Aminatu Osman, Augus...
Performance Appraisal Systems (PAS), Educational Institutions, Job Satisfaction, Organizational Commitment

This study investigates the efficacy of performance appraisal systems (PAS) in educational institut... 5 months ago

Empirical and Theological Approaches in Evangelica...
Isaac Bright Fosu Ku...
Evangelical Missions, Church Growth, Cultural Engagement, Ghanaian Context, Missiological Strategies

This comparative analysis examines the missiological approaches of Donald McGavran and Leslie Newb... 5 months ago

The Pottery-Making of Dangi and Kukuo: Ideological...
Moro, Kofi Asante-Ky...
Cultural functions, Ideologies, Indigenous, Pottery-making

The main purpose of this study was to examine the pottery-making ideologies and functions of Dangi... 5 months ago

The Role of Compensation on Job Satisfaction: A Re...
Emmanuel Poatob
Compensation, Job satisfaction, employees, financial and non-financial compensation

The relationship between pay and job satisfaction is examined in this review, with focus on how th... 6 months ago

Women in Leadership Positions, Opportunities and C...
Rashida Abdul-Rahman...
Leadership, leadership styles, glass ceiling, women leadership barriers.

In order to accomplish organizational objectives, leaders work with subordinates to influence thei... 6 months ago

Records : 20 of 2108 | Page : of 106 | Limit

Close

Search SIS !

Articles, journal, project, hall of fame

Username or Email
Password

Don't have an account? Register

Do you have an account already? Login

Copyright © Scholar Indexing Society All Rights Reserved.