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Hepatic steatosis is a common
presentation in HCV-infected individuals. Drs. Yoon and Hu review the incidence, pathogenesis, and clinical impact of
steatosis on natural history of chronic HCV infection. Co-infection of hepatitis B virus (HBV) with HCV represents
another challenge that is especially common in areas where HBV is prevalent. Drs. Liu and Hou give us an update on
this important topic.