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3717
Indexed articles
1338
Archived project
26
Indexed Journals
206
Registered users
29
visits in 24hrs
511951
Total visit count
18
Hall of fame
68
Researchers
15
Sponsors
Updating and Standardizing Covid-19 Vaccines
Eric J. Rubin, Linds...
Covid-19 vaccines, antigen updates, FDA advisory committee, NEJM audio interview, SARS-CoV-2 transmission, public health emergency, immunization schedule, vaccine strain harmonization, infectious disease guidance

This editorial summarizes an NEJM audio interview recorded on January 30, 2023, with Drs. Eric Rubin... 4 months ago

Unwinding Continuous Medicaid Enrollment
Sara Rosenbaum, Sara...
Medicaid continuous enrollment, Covid-19 emergency provisions, Consolidated Appropriations Act, coverage interruption, administrative churn, Medicaid eligibility, disenrollment risks, health equity, public health emergency

This article explores the implications of ending the continuous Medicaid enrollment provision establ... 4 months ago

Tuberculous Optochiasmatic Arachnoiditis
Carmen Amado, Karlo ...
tuberculous optochiasmatic arachnoiditis, tuberculous meningitis, paradoxical reaction, optic chiasm inflammation, ring-enhancing lesions, papilledema, antituberculosis therapy, vision loss

This brief case report presents a 29-year-old man with tuberculous optochiasmatic arachnoiditis, a r... 4 months ago

Treatment Strategy for Rifampin-Susceptible Tuberc...
Nicholas I. Paton, C...
TRUNCATE-TB trial, tuberculosis treatment strategy, bedaquiline-linezolid, rifampin-linezolid, shortened TB regimen, drug-susceptible TB, noninferiority trial, adverse events, relapse monitoring, global TB programs

   This randomized, open-label, noninferiority trial evaluates whether a treatment strateg... 4 months ago

The Path Forward for Covid-19 Therapeutics
Eric J. Rubin, Linds...
interferon lambda, Covid-19 therapeutics, SARS-CoV-2 transmission, NEJM audio interview, antiviral agents, public health emergency, emerging treatments, infectious disease updates

   This editorial summarizes an NEJM audio interview recorded on February 21, 2023, featur... 4 months ago

The Journey to RSV Vaccines — Heralding an Era o...
Barney S. Graham
RSV, prefusion F protein, fusion glycoprotein, structure-based vaccine design, monoclonal antibodies, antigenicity, protein engineering, nirsevimab, vaccine-enhanced disease, Covid-19 vaccine blueprint, neutralizing epitopes, viral fusion mechanisms

This article traces the decades-long evolution of vaccine development for respiratory syncytial viru... 4 months ago

The Path Forward for Covid-19 Therapeutics
Eric J. Rubin, Linds...
interferon lambda, oral Covid-19 therapeutics, SARS-CoV-2, public health emergency, NEJM audio interview, antiviral agents, emerging treatments, infectious disease updates

This editorial summarizes an audio interview with NEJM editors discussing prospects for emerging Cov... 4 months ago

The Expanding Arsenal of Oral Agents to Treat Covi...
Eric J. Rubin, Linds...
oral Covid-19 therapeutics, nirmatrelvir, VV116, antiviral agents, outpatient treatment, SARS-CoV-2, public health emergency, NEJM audio interview, Covid-19 transmission, infectious disease updates

This editorial summarizes an audio discussion among NEJM editors reviewing progress and prospects in... 4 months ago

Substantial Neutralization Escape by SARS-CoV-2 Om...
Jessica Miller, Nico...
BQ.1.1, XBB.1, SARS-CoV-2, neutralization escape, Omicron subvariants, R346T mutation, mRNA booster, bivalent vaccine, immune evasion, CD8+ T-cell response, pseudovirus assay, WA1/2020 strain

This study assessed the neutralization resistance of SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.1... 4 months ago

Splenic Tuberculosis
Chung-Yen Chen, Po-J...
splenic tuberculosis, HIV, granulomatous inflammation, caseous necrosis, acid-fast bacilli, Mycobacterium tuberculosis, CD4 count, real-time PCR, necrotic nodules, abdominal pain, E-Da Hospital, Taiwan

   A 29-year-old man with HIV presented with a 2-week history of left-sided abdominal pain... 4 months ago

Shortening Tuberculosis Treatment — A Strategic ...
Véronique Dartois, ...
TRUNCATE-TB trial, tuberculosis, shortened treatment, bedaquiline, linezolid, adaptive trial design, drug resistance, noninferiority, treatment strategy, global health, regimen toxicity, implementation barriers, directly observed therapy, logistic burden

   This editorial discusses the TRUNCATE-TB trial, which tested a strategic approach to sh... 4 months ago

Respiratory Syncytial Virus Prefusion F Protein Va...
Alberto Papi, Michae...
RSVPreF3 OA, respiratory syncytial virus, RSV vaccine, older adults, prefusion F protein, adjuvanted vaccine, acute respiratory infection, lower respiratory tract disease, vaccine efficacy, RSV subtype A/B, coexisting conditions

This international phase 3 trial evaluated the efficacy and safety of a single dose of an adjuvanted... 4 months ago

Protection against Reinfection with the Omicron BA...
Hiam Chemaitelly, Pa...
BA.2.75 subvariant, SARS-CoV-2 reinfection, hybrid immunity, test-negative design, vaccine efficacy, immune evasion, Qatar, Covid-19, Omicron BA.1, BA.2, BA.4, BA.5, immune imprinting, national health database

This correspondence analyzes the real-world effectiveness of prior SARS-CoV-2 infections in preventi... 4 months ago

Protecting the Legitimacy of Medical Expertise
Richard J. Baron, Ca...
medical licensing boards, misinformation, ivermectin, Covid-19, professional discipline, Right to Try Act, FDA authority, expertise erosion, medical regulation, judicial challenges, public trust, empirical evidence

This article examines the growing threats to the authority and regulatory power of medical licensing... 4 months ago

Progress in Treating a Neglected Tropical Disease
David H. Walker, Luc...
scrub typhus, INTREST trial, azithromycin, doxycycline, neglected tropical diseases, Orientia tsutsugamushi, vector-borne illness, point-of-care diagnostics, vaccine development challenges, super-neglected diseases, global health

This editorial discusses the INTREST clinical trial evaluating intravenous azithromycin, doxycycline... 4 months ago

Periprosthetic Joint Infection
Robin Patel
periprosthetic joint infection, PJI, arthroplasty-associated infection, biofilm, coagulase-negative staphylococci, S. aureus, sonication, alpha-defensin, debridement and implant retention (DAIR), two-stage revision, one-stage revision

Periprosthetic joint infection (PJI) is a biofilm-driven, prosthesis-specific condition distinct fro... 4 months ago

Oral Vancomycin as Secondary Prophylaxis for Preve...
Leslie L. Chang, Jes...
oral vancomycin prophylaxis, recurrent C. difficile infection, fidaxomicin, microbiome disruption, UTIs, neurogenic bladder, prophylactic antibiotics, Clinical Decisions, gut microbiota, secondary prevention

This Clinical Decisions piece presents a vignette of a 72-year-old woman with quadriplegia, neurogen... 4 months ago

Odontogenic Cutaneous Fistula
Jianqiu Jin, Yuxing ...
odontogenic fistula, cutaneous fistula, dental trauma, mandibular incisor, osteolysis, periapical rarefaction, skin dimpling, root canal, clinical image, misdiagnosis risk

A 42-year-old woman presented with swelling and pain on the right side of her chin, without dental s... 4 months ago

Neutralization of BQ.1, BQ.1.1, and XBB with RBD-D...
Dedong Li, Minrun Du...
ZF2001 vaccine, RBD-dimer, BQ.1, BQ.1.1, XBB, immune escape, Delta–BA.2 heterodimer, pseudovirus neutralization, next-generation vaccine, SARS-CoV-2 spike mutations, China, FRNT50 assay, COVID-19 booster

   This correspondence reports on the neutralization capacity of ZF2001 (homotypic RBD-dim... 4 months ago

Neutralization of BA.4–BA.5, BA.4.6, BA.2.75.2, ...
Zou J, Kurhade C, Pa...
bivalent vaccine, BA.4–BA.5 booster, omicron sublineages, SARS-CoV-2, FRNT50, XBB.1, BA.2.75.2, BQ.1.1, vaccine-induced immunity, neutralizing antibodies, breakthrough infection, GMFI comparison

This clinical letter compares neutralizing antibody responses in adults ≥55 years after receiving ... 4 months ago

Records : 120 of 3665 | Page : of 184 | Limit

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