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The 2021 Reauthorization of CAPTA — Letting Publ...
Margaret H. Lloyd Si...
CAPTA, child welfare, substance use disorder, prenatal substance exposure, family care plans, health equity, public health, child protective services, opioid crisis

This Perspective article evaluates the 2021 reauthorization of the Child Abuse Prevention and Treatm... 1 week ago

Striae and an Adrenal Mass
Jennifer H. Yo, M.B....
Adrenocortical carcinoma, Cushing’s syndrome, HELLP syndrome, pregnancy, striae, hypertension, hypokalemia, mitotane

This case report describes a 27 year old primigravid woman presenting with new-onset diabetes, hyper... 1 week ago

Venous Thrombosis during Spaceflight
Serena M. Auñón-Ch...
spaceflight, venous thrombosis, internal jugular vein, astronaut health, anticoagulation, apixaban, enoxaparin, telemedicine, ultrasound imaging, NASA medicine

This correspondence describes the diagnosis and treatment of a left internal jugular vein thrombosis... 1 week ago

Vericiguat — Another Victory for Targeting Cycli...
John C. Burnett Jr.
vericiguat, cyclic GMP, guanylyl cyclase, nitric oxide, VICTORIA trial, natriuretic peptides, heart failure, cardiovascular pharmacology, precision medicine, NT-proBNP

This editorial discusses the molecular basis and therapeutic promise of cyclic GMP modulation in hea... 1 week ago

Stress Incontinence in Women
Jennifer M. Wu, M.D...
Stress urinary incontinence, pelvic-floor muscle training, midurethral sling, pessary, obesity, Kegel exercises, urodynamic testing, surgical management

This clinical practice article addresses the evaluation and management of stress urinary incontinenc... 1 week ago

Spermatogonium-Derived Complete Hydatidiform Mole
Hirokazu Usui, M.D....
Complete hydatidiform mole, spermatogonium, round spermatid injection, androgenetic, gestational trophoblastic neoplasia, assisted reproductive technology, imprinting

This brief report describes a rare case of a complete hydatidiform mole (CHM) derived from a spermat... 1 week ago

Vericiguat in Patients with Heart Failure and Redu...
Paul W. Armstrong, B...
vericiguat, heart failure, reduced ejection fraction, soluble guanylate cyclase, VICTORIA trial, cardiovascular outcomes, hospitalization, randomized trial, NT-proBNP, high-risk heart failure

This phase 3, randomized, double-blind, placebo-controlled trial (VICTORIA) evaluated the efficacy a... 1 week ago

Recurrent Ovarian Cancer — Sculpting a Promising...
Ginger J. Gardner, D...
Recurrent ovarian cancer, cytoreductive surgery, DESKTOP III, personalized medicine, surgical oncology, platinum-sensitive relapse

This article is an editorial discussing recent randomized trials evaluating secondary cytoreductive ... 1 week ago

Randomized Trial of Fetal Surgery for Severe Left ...
J.A. Deprest, K.H. N...
Fetal surgery, congenital diaphragmatic hernia, FETO, neonatal survival, prenatal intervention, randomized trial

In fetuses with severe left congenital diaphragmatic hernia (CDH), fetoscopic endoluminal tracheal o... 1 week ago

Randomized Trial of Cytoreductive Surgery for Rela...
P. Harter, J. Sehoul...
Cytoreductive surgery, recurrent ovarian cancer, chemotherapy, overall survival, platinum-sensitive,

reatment for patients with recurrent ovarian cancer has been mainly based on systemic therapy. The r... 1 week ago

Vericiguat in Patients with Heart Failure and Redu...
Paul W. Armstrong, B...
vericiguat, heart failure, reduced ejection fraction, soluble guanylate cyclase, VICTORIA trial, cardiovascular outcomes, hospitalization, randomized trial, NT-proBNP, high-risk heart failure

This phase 3, randomized, double-blind, placebo-controlled trial (VICTORIA) evaluated the efficacy a... 1 week ago

Risk Prediction for Acute Kidney Injury — Super ...
Frank Tacke
acute kidney injury, suPAR, kidney biomarkers, podocyte injury, inflammation, risk prediction, angiography, critical care, renal failure, clinical editorial

This editorial evaluates the clinical implications of using soluble urokinase plasminogen activator ... 1 week ago

Renin–Angiotensin–Aldosterone System Blockers ...
Giuseppe Mancia, Fed...
Covid-19, ACE inhibitors, ARBs, RAAS blockers, hypertension, cardiovascular risk, case-control study, SARS-CoV-2, drug safety, Lombardy study

This large population-based case-control study evaluated whether angiotensin-converting enzyme (ACE)... 1 week ago

Reduced Rate of Hospital Admissions for Acute Coro...
Ovidio De Filippo, F...
COVID-19, acute coronary syndrome, hospital admissions, Northern Italy, STEMI, NSTEMI, cardiac emergencies, public health impact, healthcare access, lockdown effect

This multicenter retrospective study evaluated hospital admission rates for acute coronary syndrome ... 1 week ago

Reduced Leaflet Motion after Transcatheter Aortic-...
Ole De Backer, Georg...
TAVR, leaflet thickening, rivaroxaban, antithrombotic strategy, bioprosthetic valve, subclinical thrombosis, CT imaging, GALILEO-4D, anticoagulation risk, prosthetic valve motion

This substudy of the GALILEO trial investigated whether a rivaroxaban-based antithrombotic strategy ... 1 week ago

Preexcited Atrial Fibrillation after a Blood Draw
David A. McNamara, M...
Wolff–Parkinson–White syndrome, preexcited atrial fibrillation, delta waves, accessory pathway, electrophysiology, procainamide, wide-complex tachycardia, syncope, case report, catheter ablation

This clinical image report describes a 33-year-old man who developed palpitations and syncope during... 1 week ago

Polymer-based or Polymer-free Stents in Patients a...
Stephan Windecker, ...
high bleeding risk, PCI, drug-eluting stents, zotarolimus, umirolimus, dual antiplatelet therapy, randomized trial, stent thrombosis, target-lesion failure, ONYX ONE

This multicenter, randomized, single-blind trial compared the safety and effectiveness of polymer-ba... 1 week ago

Pneumocephalus Due to a Bronchoatrial Fistula
Alan Zakko, Hira Bak...
pneumocephalus, bronchoatrial fistula, lung cancer, air embolism, cavitary lesion, CT imaging, squamous-cell carcinoma, neurological emergency, pulmonary fistula, ICU mortality

This clinical image report describes a 61-year-old man with stage IIIB squamous-cell lung carcinoma ... 1 week ago

Out-of-Hospital Cardiac Arrest during the Covid-19...
Enrico Baldi, Giusep...
Covid-19, out-of-hospital cardiac arrest, OHCA, Lombardy, emergency services, Italy, bystander CPR, mortality, SARS-CoV-2, public health impact

This correspondence investigates the correlation between the Covid-19 outbreak and out-of-hospital c... 1 week ago

Native-Valve Infective Endocarditis
Henry F. Chambers, A...
infective endocarditis, native valve, Duke criteria, echocardiography, Enterococcus faecalis, Staphylococcus aureus, antimicrobial therapy, surgery, culture-negative endocarditis, nephrotoxicity

This comprehensive clinical review discusses native-valve infective endocarditis (IE), emphasizing i... 1 week ago

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