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Neutralization against BA.2.75.2, BQ.1.1, and XBB ...
Davis-Gardner ME, La...
bivalent booster, omicron subvariants, BA.2.75.2, BQ.1.1, XBB, SARS-CoV-2, neutralization efficiency, FRNT50 titers, vaccine-escape mutation, R346T, antibody response, booster comparison, Emory cohort

This serologic study evaluates live-virus neutralization of emergent SARS-CoV-2 omicron subvariants ... 6 months ago

Neonatal Herpes Simplex Virus Infection
Mantecón L, Solís ...
neonatal HSV-1, vesicular rash, intrauterine infection, herpes simplex virus, premature delivery, maternal transmission, acyclovir treatment, developmental outcome, Images in Clinical Medicine

This clinical vignette describes a premature infant born at 32 weeks gestation who presented with ve... 6 months ago

MPXV Transmission at a Tattoo Parlor
Viedma-Martinez M, D...
monkeypox virus, mpox, tattoo parlor outbreak, direct inoculation, piercing-related transmission, non-sexual transmission, public health investigation, lymphadenopathy, cutaneous necrosis, Spain outbreak

This letter to the editor describes a cluster of 21 mpox (MPXV) cases traced to piercing or tattooin... 6 months ago

Malaria — Epidemiology, Treatment, and Preventio...
Surgo Ventures, New ...
malaria, public health storytelling, rural health, vector control, vaccine development, drug pipeline, health communication, Perspective article, Double Take video, community engagement

This multimedia Perspective includes a short narrative titled Venkamma's Dowry and an accompanying â... 6 months ago

Investing in National HIV PrEP Preparedness
Jeremiah Johnson, Am...
PrEP, HIV prevention, health equity, public health infrastructure, uninsured access, generic TDF-FTC, lab pricing, telehealth, hub-and-spoke model, Black health disparities, national HIV strategy, marginalized populations

This Perspective article argues that the U.S. has failed to develop public health infrastructure cap... 6 months ago

Intravenous Doxycycline, Azithromycin, or Both for...
G.M. Varghese, D. Da...
scrub typhus, intravenous antibiotics, doxycycline, azithromycin, combination therapy, randomized trial, organ involvement, fever defervescence, PCR negativity, Orientia tsutsugamushi, India, INTREST trial

   This multicenter, double-blind, randomized trial (INTREST) compared intravenous doxycyc... 6 months ago

Influenza Vaccine in Pediatric Recipients of Hemat...
Jennifer E. Schuster...
high-dose influenza vaccine, HD-TIV, quadrivalent influenza vaccine, SD-QIV, pediatric HCT, hemagglutination-inhibition titers, immunogenicity, vaccine safety, injection-site reactions, influenza A antigens

This Perspective article argues that the U.S. has failed to develop public health infrastructure cap... 6 months ago

Immunologic Effect of Bivalent mRNA Booster in Pat...
Luca Huth, Luise Sch...
bivalent mRNA booster, hemodialysis, anti-spike IgG, BA.4, BA.5, antibody avidity, breakthrough infection, booster immunogenicity, neutralization activity, hybrid immunity

   This correspondence reports on a case series of 55 hemodialysis patients who had receiv... 6 months ago

Immunogenicity of a Fourth Homologous Dose of NVX-...
Katia Alves, Joyce S...
NVX-CoV2373, Novavax, fourth dose, booster, recombinant spike protein, IgG titers, neutralization titers, antigenic cartography, Matrix-M adjuvant, cross-reactive immunity, Omicron variants, BA.1, BA.5

This correspondence presents results from an extension of a phase 2 randomized trial evaluating the ... 6 months ago

Health Care in U.S. Correctional Facilities — A ...
Marcella Alsan, Crys...
correctional health care, Estelle v. Gamble, Prison Litigation Reform Act, constitutional rights, deliberate indifference, Eighth Amendment, Americans with Disabilities Act, health disparities, Medicaid exclusion, federal oversight

This Perspective explores the precarious legal and operational status of health care in U.S. correct... 6 months ago

Hard to Swallow
Daniel Jacobs, Dora ...
CMS, Universal Foundation, quality measurement, care transformation, health equity, interagency collaboration, outcome alignment, patient-centered metrics, public health strategy, diagnostic vigilance

This Perspective from CMS leaders discusses the alignment of quality measures across federal program... 6 months ago

Gastrointestinal Kaposi’s Sarcoma
Deniz E. Tekcan Sanl...
Kaposi’s sarcoma, HIV, gastrointestinal lesions, endoscopy, biopsy, CD4 count, viral load, CMV colitis, COVID-19 pneumonia, immunosuppression

A previously healthy 54-year-old man presented with bloody diarrhea and cutaneous lesions. Examinati... 6 months ago

Facing the New Covid-19 Reality
Wafaa M. El-Sadr, As...
Covid-19 transition, public health strategy, vaccine equity, health disparities, sentinel surveillance, pandemic fatigue, SARS-CoV-2 variants, tailored guidance, community trust, health communication

This Perspective reflects on the evolving impact of Covid-19 and advocates for nuanced public health... 6 months ago

Evaluation of BNT162b2 Covid-19 Vaccine in Childre...
Flor M. Muñoz, Lawr...
BNT162b2, Covid-19 vaccine, children under 5, pediatric vaccination, immunobridging, vaccine efficacy, safety profile, neutralizing titers, Omicron, SARS-CoV-2, placebo-controlled trial, MIS-C, FDA authorization

This clinical study assesses the safety, immunogenicity, and efficacy of a three-dose 3-µg BNT162b2... 6 months ago

End of a Declared Public Health Emergency — Impl...
Peter W. Marks, Hila...
Public Health Emergency, EUA, Covid-19, FDA, Section 319, Section 564, emergency use, regulatory approval, chloroquine, hydroxychloroquine, vaccines, therapeutics, clinical trials

This Perspective outlines how the termination of a declared Public Health Emergency (PHE) in the U.S... 6 months ago

Efficacy of Antiviral Agents against Omicron Subva...
Masaki Imai, Mutsumi...
Omicron subvariants, BQ.1.1, XBB, monoclonal antibodies, immune evasion, antiviral efficacy, remdesivir, molnupiravir, nirmatrelvir, FRNTâ‚…â‚€, ICâ‚…â‚€

This correspondence assesses the effectiveness of monoclonal antibodies and antiviral drugs against ... 6 months ago

Efficacy and Safety of an Ad26.RSV.preF–RSV preF...
Ann R. Falsey, Krist...
Ad26.RSV.preF, RSV preF protein, respiratory syncytial virus, older adults, vaccine efficacy, T-cell response, neutralizing antibodies, phase 2b trial, CYPRESS, RSV-mediated respiratory disease

This phase 2b, randomized, double-blind, placebo-controlled trial (CYPRESS) evaluated the efficacy, ... 6 months ago

Effectiveness of a Meningococcal Group B Vaccine (...
J. Castilla, M. Garc...
meningococcal serogroup B, 4CMenB, Bexsero, vaccine effectiveness, invasive meningococcal disease, matched case-control study, pediatric immunization, genetic MATS typing, serogroup coverage, public health surveillance

This nationwide matched case-control study evaluated the effectiveness of the four-component meningo... 6 months ago

Early Treatment with Pegylated Interferon Lambda f...
Gilmar Reis, Eduardo...
pegylated interferon lambda, Covid-19, SARS-CoV-2, adaptive platform trial, outpatient treatment, antiviral therapy, vaccination status, hospitalization reduction, viral load, phase 3 trial

This phase 3, randomized, placebo-controlled trial evaluates the efficacy of a single dose of pegyla... 6 months ago

Drug Sensitivity of Currently Circulating Mpox Vir...
Denisa Bojkova, Marc...
mpox virus, antiviral drug sensitivity, tecovirimat, cidofovir, brincidofovir, IC50, DNA polymerase mutation, viral replication, cytopathic effects, human cell cultures

This correspondence letter evaluates the drug sensitivity of currently circulating mpox virus isolat... 6 months ago

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