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Efruxifermin in Compensated Liver Cirrhosis Caused...
Mazen Noureddin, Mar...
Efruxifermin, MASH (metabolic dysfunction-associated steatohepatitis), liver cirrhosis, FGF21 analogue, fibrosis reduction, compensated cirrhosis, clinical trial, metabolic liver disease

This phase 2b randomized, double blind, placebo controlled trial evaluated the efficacy and safety o... 4 months ago

Mpox in Pregnancy — Risks, Vertical Transmission...
Jean B. Nachega, Emm...
mpox, monkeypox virus (MPXV), pregnancy, vertical transmission, fetal demise, maternal mortality, clade I MPXV, clade IIb MPXV, tecovirimat, MVA-BN vaccine, LC16m8 vaccine, breast-feeding, zoonotic disease

This Perspective outlines the clinical, epidemiologic, and public health implications of mpox (monke... 4 months ago

Effects of Food and Nutrition Insecurity on Global...
Effects of Food and ...
Food insecurity, nutrition insecurity, malnutrition, global health, hunger, poverty, health disparities, food security interventions, maternal and child health, chronic disease

This review examines the profound global health impacts of food and nutrition insecurity, affecting ... 4 months ago

Discovery of GLP-1–Based Drugs for the Treatment...
Daniel J. Drucker, M...
GLP-1 receptor agonists, obesity treatment, glucagon-like peptide-1, liraglutide, semaglutide, tirzepatide, diabetes, weight loss, metabolic benefits

This article chronicles the scientific and clinical breakthroughs behind GLP1 based drugs, which hav... 4 months ago

Long-Distance Spread of a Highly Drug-Resistant Ep...
Julie Figoni, Caroli...
cholera, Vibrio cholerae O1 El Tor, AFR13 sublineage, IncC plasmid, antimicrobial resistance, azithromycin resistance, ciprofloxacin resistance, cephalosporin resistance, plasmid pYA00120881, plasmid pCNRVC19024

This correspondence documents the transcontinental spread of a highly drug-resistant seventh-pandemi... 4 months ago

Long Covid Defined
E. Wesley Ely, Lisa ...
long Covid, NASEM definition, infection-associated chronic condition, post-acute sequelae, SARS-CoV-2, systemic disease, relapsing-remitting symptoms, organ system involvement, postexertional malaise

This Sounding Board article presents the 2024 National Academies of Sciences, Engineering, and Medic... 4 months ago

Coadministered Cagrilintide and Semaglutide in Adu...
W.T. Garvey, M. Blü...
Cagrilintide, Semaglutide, Obesity, Weight Loss, Cardiometabolic Risk, GLP-1 Agonist, Amylin Analogue, Randomized Controlled Trial

This phase 3a trial evaluated the efficacy and safety of coadministered cagrilintide and semaglutide... 4 months ago

Choice of Intravenous Fluid for Resuscitation in D...
Suellen Li, Bassem M...
Diabetic Ketoacidosis, Fluid Resuscitation, Balanced Crystalloids, Isotonic Saline, Hyperchloremic Acidosis, Electrolyte Management, Clinical Guidelines

This clinical decision article explores the debate over intravenous fluid choice for resuscitation i... 4 months ago

Levofloxacin Preventive Therapy for Persons Expose...
Susan E. Dorman
levofloxacin, MDR tuberculosis, tuberculosis prevention, chemoprevention, VQUIN MDR trial, TB-CHAMP trial, fluoroquinolone resistance, delamanid, WHO guidelines, household contacts

   This editorial discusses the emerging role of levofloxacin as preventive therapy for in... 4 months ago

Lemierre’s Syndrome Complicated by Cavernous Sin...
Matthew J. Heron, Fr...
Lemierre’s syndrome, cavernous sinus thrombosis, oculomotor nerve palsy, ptosis, diplopia, internal jugular vein thrombosis, Fusobacterium necrophorum, septic thrombophlebitis, CT venography, MRI, antimicrobial therapy

This clinical image report describes a 20-year-old woman who presented with headache, diplopia, and ... 4 months ago

Chemical Complexity of Food and Implications for T...
Nutrition Dark Matt...
Giulia Menichetti, Albert-László Barabási, Joseph Loscalzo

Poor nutrition is a leading cause of illness and mortality, contributing to preventable diseases suc... 4 months ago

Keeping SNAP in Line with Global Evidence on Food ...
Benjamin W. Chrising...
SNAP, Supplemental Nutrition Assistance Program, food security, nutrition policy, item restrictions, sugar-sweetened beverages, Healthy Incentives Pilot, GusNIP, cash transfers, food vouchers, global evidence, chronic disease

This perspective critiques recent U.S. Congressional proposals to impose nutrition-based restriction... 4 months ago

Intertriginous Rash in Secondary Syphilis
Mati Chuamanochan, J...
secondary syphilis, intertriginous rash, systemic lupus erythematosus (SLE), immunosuppression, hydroxychloroquine, prednisolone, Treponema pallidum, hemagglutination assay, rapid plasma reagin (RPR)

This clinical image report describes a 25-year-old woman with systemic lupus erythematosus (SLE) who... 4 months ago

Influenza A(H5N1) Virus Infection in Two Dairy Far...
Jennifer Morse, Jose...
HPAI A(H5N1), avian influenza, dairy farm workers, zoonotic transmission, conjunctivitis, respiratory symptoms, genotype B3.13, clade 2.3.4.4b, nasopharyngeal swab, conjunctival swab, RT-PCR, coronavirus 229E

This correspondence describes two confirmed cases of highly pathogenic avian influenza (HPAI) A(H5N1... 4 months ago

Cagrilintide–Semaglutide in Adults with Overweig...
Melanie J. Davies, ...
Cagrilintide, Semaglutide, Obesity, Type 2 Diabetes, Weight Management, Glycemic Control, Randomized Controlled Trial

This phase 3a, double-blind, randomized, placebo-controlled trial evaluated the efficacy and safety ... 4 months ago

Beyond Glucocorticoids for IgG4-Related Disease
Robert Spiera
IgG4-related disease, glucocorticoids, inebilizumab, B-cell depletion, rituximab, immunosuppressive therapy, MITIGATE trial

This editorial evaluates emerging treatments for IgG4 related disease, a fibroinflammatory condition... 4 months ago

Automated Insulin Pump in Type 2 Diabetes
Betul Hatipoglu
Type 2 diabetes, automated insulin delivery (AID), insulin pump, continuous glucose monitoring (CGM), glycemic control, diabetes technology

This editorial discusses the efficacy and safety of automated insulin delivery (AID) systems for typ... 4 months ago

Advancing Transgender Health amid Rising Policy Th...
David R.A. Coelho, ...
Transgender health, gender-affirming care, health policy, LGBTQ+ rights, discrimination, mental health, equity

This perspective article examines the escalating policy threats to transgender health under the Trum... 4 months ago

Immunobridging for Pemivibart, a Monoclonal Antibo...
Pete Schmidt, Yong L...
pemivibart, monoclonal antibody, Covid-19 prophylaxis, immunobridging, CANOPY trial, adintrevimab, delta variant, JN.1 variant, IC50, neutralizing titers, Emergency Use Authorization (EUA), immunocompromised patients

This correspondence outlines the immunobridging methodology used to support the Emergency Use Author... 4 months ago

Acquired Osteomalacia Associated with Autoantibod...
Yoshitomo Hoshino, K...
Osteomalacia, autoantibodies, PHEX, FGF23, hypophosphatemia, autoimmune disease, tumor-induced osteomalacia

This study identified autoantibodies against PHEX (phosphate-regulating endopeptidase Xlinked) in pa... 4 months ago

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